Water quality is a medical issue

The Cost of Bad Water

Purifying water to medical grade costs $2. The dialysis you need when your kidneys fail costs $50.

The world spends $350 billion a year on water infrastructure, and almost none of it reaches clinical-grade purification. In sub-Saharan Africa, 9 in 10 people who need dialysis never receive it.

Dialysis costs 25× the water purification step that precedes it

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People with chronic kidney disease worldwide
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Cost of one RO unit (serves an entire center)
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Of ESKD patients discontinue dialysis in sub-Saharan Africa

One center for six million.

Grateful to the leadership at Amoud Foundation for hosting me in Jigjiga, Ethiopia in late 2025. I went to look at the healthcare infrastructure. I didn’t expect to spend most of my time thinking about water.

The dialysis center there serves six million people. It has eleven working machines and four broken ones. There are thirty patients currently in treatment and eighty-five on a waiting list.

Each patient needs treatment three times a week, four hours each session. That’s a 12-hour commitment, every week, for the rest of their life. When a machine breaks there’s often no one to fix it. The technicians who get trained leave for better jobs in other countries.

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Working machines
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Broken machines
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Patients treated
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On the waitlist

A partnership with the regional government subsidizes treatment so patients pay $5 per session instead of the full $50 cost.

The dialysis center in Jigjiga, eastern Ethiopia

Jigjiga dialysis center, October 2025 field assessment. Pictured: Amoud Foundation President Mohamoud Egal, Executive Director Issam Abdallah, Ethiopia Country Director Abdul Kadir, and Mazhar Memon of CharitySense, alongside dialysis medical and executive staff.

Bad water is a big problem

In parts of eastern Ethiopia, tap water runs at 1,380 ppm total dissolved solids, nearly 3x what the EPA considers safe for drinking. The dialysis team in Jigjiga explained what that does to a body over time: kidneys filter dissolved minerals from blood, and when the mineral load stays chronically high, excess calcium, fluoride, and other minerals deposit as microscopic crystals in the kidney tubules, causing scarring and slow loss of function.

Fluoride is a major part of the problem. A global hazard map estimates 180 million people are exposed to unsafe fluoride levels in groundwater. The Ethiopian Rift Valley is one of the worst-affected regions: groundwater fluoride reaches 7.8 to 18 mg/L, up to 12x the WHO limit, and up to 8 million people drink it daily.

Researchers call the pattern chronic kidney disease of unknown etiology (CKDu). In Sri Lanka, studies found fluoride in 99% of wells in CKDu-endemic areas and linked water hardness to disease prevalence. The pattern repeats wherever high-mineral groundwater is the primary drinking source.

Not all kidney disease comes from water. Diabetes and high blood pressure are the two largest drivers globally. The Global Burden of Disease Study 2023 identified them as the leading risk factors. But in regions with high-TDS water, water quality adds a third compounding cause that most water infrastructure programs aren’t built to address.

A crisis that doubled in 30 years

Chronic kidney disease now affects nearly 800 million adults worldwide, more than double the number in 1990. It is the ninth leading cause of death globally, killing nearly 1.5 million people per year.

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Adults with CKD worldwide
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Deaths per year

According to The Lancet Global Health, 84% of newly diagnosed end-stage kidney disease patients in sub-Saharan Africa discontinue dialysis. The primary reason: they cannot pay. Most die within weeks.

CKD prevalence by region

Healthcare workforce gap

Dialysis basics

Your kidneys are a filter. When they fail, you need an external one. Three times a week, blood leaves your body, passes through a bundle of hollow fibers while a cleaning solution removes the waste from the other side, and returns. That’s it.

The dialyzer, the actual filter, contains around 15,000 fibers thinner than a human hair. Your kidneys normally process about 180 liters of blood per day. The dialyzer replicates this across four hours, processing your entire blood volume multiple times.

Arterial needleVenous needlePatient ArmArteriovenousfistulaArterialblood outBlood pump200 to 400 mL/minArterialpressureHeparininfusionDialyzer~15,000 hollow fibersblood ↓dialysate ↑Air detectorbubble trapVenouspressureVenous returnblood inUsed dialysateto drainFresh dialysate500 to 800 mL/minCountercurrentflow maximiseswaste removalacross membrane(dialysate ↑ / blood ↓)
Hemodialysis circuit: blood exits via the arteriovenous fistula, driven by a peristaltic pump, through the dialyzer and back to the patient. Inside the dialyzer, blood flows downward through roughly 15,000 hollow fibers while dialysate flows upward outside them, a countercurrent design that maximizes toxin removal across the semipermeable membrane. Heparin prevents clotting and the air detector protects against embolism. Hover components to explore.

The blood pump moves 200 to 400 mL/min. The dialysate flows at 500 to 800 mL/min, consuming about 120 liters per session. Blood out, membrane filter, blood back.

Dialysis machines at the Jigjiga dialysis center, eastern Ethiopia

The dialysis unit at Jigjiga, eastern Ethiopia. The only center serving a population of six million.

Per-session consumables (hover to explore)

Cost ranges from Karopadi et al., BMC Health Services Research 2013. Consumables account for 70 to 85% of session cost in low-income settings.

The only hard part: water quality

The cost question starts with water. Of the $50 it costs to run a session, $2 goes to purification, the most fundamental input and the one most directly linked to where patients live.

Drinking water standards sit at 500 ppm. Dialysis water has to be under 10 ppm, fifty times stricter than the drinking water standard. A single reverse osmosis unit brings that down to dialysis grade. One unit serves an entire center. It costs $5,000 to $15,000.

Tap water1,380 ppmReverse osmosis138× purerUltrapure water<10 ppmDialysate prepDialyzer67%33%RO reject, to drainBicarbonateAcid conc.Used dialysateto drain
Water treatment flow for a single hemodialysis session. Tap water at 1,380 ppm passes through reverse osmosis, yielding ultrapure water at under 10 ppm, 138 times purer. Two-thirds continues to the dialyzer as buffered dialysate; one-third is discharged as reject. Proportions based on AAMI RD52 standards. Hover nodes and ribbons to explore.
Industrial reverse osmosis water purification system

A typical RO system. Tap water enters under pressure; membranes reject dissolved solids; ultrapure water exits. Adapted from Renal Fellow Network.

Water purification setup at the Jigjiga dialysis center showing the reverse osmosis system

The RO system at Jigjiga. Source water at 1,380 ppm TDS is brought below 10 ppm for dialysis use.

Annual water system consumables (hover to explore)

Component costs based on AAMI ANSI/AAMI RD52 standards and Kasparek & Rodriguez, CJASN 2015;10:1061-1071. Annual totals vary by center size and local sourcing.

What dialysate actually is

Dialysate is the cleaning fluid on the other side of the membrane, the thing that extracts waste from blood. It’s not exotic. It’s mostly purified water mixed with table salt, baking soda, potassium, calcium, magnesium, and a little glucose.

The concentrations matter precisely. But precision here is a mixing problem, not a sourcing problem. A proportioning pump blends two off-the-shelf concentrates with purified water at roughly 1:34.

Ingredient cost per session (hover to explore)

Estimated raw ingredient costs per session. In practice, dialysate is purchased as pre-mixed acid and bicarbonate concentrates ($1 to $3 combined). Source: Karopadi et al., BMC Health Services Research 2013.

What a session actually costs

Ethiopia (actual cost)$50
Most African countries$100 to $150
United States$300 to $500

Cost per session breakdown

At $50 per session, a patient needs $7,800 per year (3x/week, 52 weeks). In the US, the USRDS estimates annual per-patient costs above $90,000. Medicare spends $36 billion per year on end-stage kidney disease alone.

Where the money goes

Consumables (dialyzer, tubing, needles, saline) account for 70 to 85% of total costs in low-income settings. They are manufactured plastic and basic chemistry. The machines are a one-time cost.

Tying it all together

What’s missing is coordination. Water infrastructure funding is scoped to access, not purification grade. Health funding is scoped to drugs and equipment, not infrastructure. The two systems don’t talk to each other, and dialysis centers fall in the gap between them.

Water Purification

One RO system can serve an entire center. Solar power is making electricity less of a constraint.

$5,000 to $15,000 one-time (clinic estimate)

Local Consumables

Dialyzers and tubing are manufactured plastic. Regional manufacturing partnerships could cut costs significantly.

Very few items need importing

Technician Retention

Four broken machines because trained techs leave. Modest stipends above market rate change the math.

Cheaper than retraining

Partnerships Over Purchases

Diaspora-led organizations are already connecting overseas resources to local clinics. Equipment manufacturers, water companies, and regional governments are the other pieces.

<$200K total center setup (field estimate)

Dialysis due to bad water is cheap to prevent.

The $2 cost of water purification targets dialysis grade: under 10 ppm. Bringing tap water down to safe drinking levels (500 ppm) costs less and reduces the mineral load that researchers link to kidney damage over time.

Organizations like Splash already focus on water quality and its downstream health effects.

Water infrastructure is usually framed as an access problem. In eastern Ethiopia, access already exists. The problem is what’s in the water. Investment in quality (mineral filtration, TDS reduction) is also investment in kidneys that won’t fail a decade from now.

Fixing water quality now means fewer people needing much more expensive interventions later.

Disclosure: Field assessment graciously organized and facilitated by Amoud Foundation. CharitySense received no compensation of any kind and has no affiliation with any organization mentioned.

Sources & Further Reading

Mazhar Memon

Mazhar Memon

Founder, CharitySense

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